Requested budget: 500.000 EUR

TWREEC deserves HORIZON-EIC 2023 prize for its devoted environmental and 17SDG2030 UN Agenda Goals research in Pakistan. Amongst the international climate research and consulting organizations ’’Third World Resources, Energy and Environment CenterTWREEC’’ www.twreec.org is perhaps the first one established by Rashid Ahmed – an international hydrocarbon-hydrological engineer of Pakistan during the year 1990 motivated by that time unrealized looming concern that two vital natural resources (HC and HYDRO) of the earth planet are at head on collision course in socioeconomic service to humanity. Others like; ‘’Green Cross International’’ in Europe, ‘’Climate Reality', ‘’Water Keeper’’, and ‘’ICE911 now Polar Ice’’ from USA entered the anti-global warming struggle years later than TWREEC – Sialkot, Pakistan. Mission of these esteemed organizations corresponds to green economy transition, air pollution control, water resources protection, and prevention of continental/polar climate ice melt. European and American research organizations quickly attained powerful world status of ‘Climate Campaigners’ as their updates sent to TWREEC regularly indicate. Paradoxically, TWREEC, comprehending the full range CCM & CCA functions for developing countries and exceptional R&D/R&I for the entire world continues pondering about sustenance but somehow continuing its projects for 17SDG2030 UN Agenda of Paris Climate Accord 2015. TWREEC, Sialkot – Pakistan, prior to international climate treaty or Paris Agreement – PA2015 have rigorously been engaged in socioeconomic affairs in compliance with requirements of 20th century environment.

Applicant: Third World Resources, Energy & Environment Centre (pvt) - TWREEC

Requested budget: 2.999.146 EUR

The COVID-19 pandemic revealed how unprepared the world was to rapidly develop a treatment against such a large-scale pandemic. To this day, no effective therapeutics has been licensed, and over 3.4 Million people died from the disease. The Openmind Antisense consortium aims to develop technology platforms that allow rapid design and deployment of antiviral antisense oligonucleotide (ASO) drugs and delivery technologies targeting respiratory viruses. Our methodology will apply not only for COVID-19, but also to other respiratory viruses. We are proposing innovative and out of the box solutions for using ASO specifically targeting viral genes of SARS-CoV-2. One of our suggested technologies is to use the sequence of the N protein RNA, linked to the RNA sequence of another virus, (Brucella bacteriophage) that will serve to direct the ASO to the target. As far as we know, no one in the world is offering to use such am advanced technology for fighting COVID-19. We will investigate a number of delivery methodologies, including lipids, peptide-based nanoparticles and Peptide Nucleic Acid “PNA” ASOs. The most promising drug formulations will advance to a nebulization test bed and to in-vivo testing. Beyond these innovations, our consortium's members bring proven experience in drug design, delivery and translational medicine. Particularly noteworthy is Prof. Chezy Barenholz, one of the main inventors and developer of the first FDA approved nano-drug (Doxil, in Europe referred to as Caelyx). Within two years Openmind Antisense will have a robustly established proof of principle for rapid and safe delivery of novel ASO inhibitors of SARS-CoV-2 to the infected lungs. Follow-up work will focus on the advancement to clinical trials and explore wideranging possibilities for future therapeutic development for a variety of viral diseases. The successful conclusion of this project will be a significant contribution to the health and economic wellbeing of the EU and beyond.

Applicant: National University of Ireland, Galway

Requested budget: 2.639.750 EUR

TWREEC proposal addresses CCM-CCA actions vital for scale-up of terrestrial ecosystems worldwide. Env.21st SET is complex function of all technologies whether in practice or abandoned due to outdating. Existing project facilities pertaining to real time technologies whether improved, advanced, or abolished may present different situations of LULUC in various countries. Exception can be quoted in urbanization, while other socioeconomic sectors may present vast opportunities of LULUC liberation from SED. SET. Agriculture is venue shifting sector, while irrigation/hydro-power infrastructure flexible in pursuance. Other infrastructure related land/air/ navigational transportation systems may present altogether LULUC challenge, and comparable is the case with mining, minerals, and industrial sectors. Accordingly, scale-up concept varies with dominant focus within urban settlement. Scaling-up ecosystems can hardly be attempted beyond ‘compensatory biome’ in urban and suburban areas. Such biomes are generated on fertile or unfertile sites as supplementary ecosystems’. Beyond suburbs, depending upon national determination it is liberation of LULUC unnecessarily confiscated by national socioeconomic sectors and transformation to LULUCF. Both types of scale-up have never been attempted in any country of the world but are the exclusive nature-based climate change mitigation and adaptation – NB.CCMA. Industrial climate change mitigation/adaptation – IN.CCMA is extremely risky and cannot compete with NB.CCMA for national survival. Geo-engineering is exclusively for climate change mitigation –CCM. Besides being expensively risk, success or failure of GE-CCM can lead to unpredictable adversities on NB.CCMA efforts in almost every country. All nature, industrial, and geo-engineering based –NIGEB interactions shall be addressed for development of NB-CCMA technology during the 24 months period in collaboration with 3 EU Partners subject to generous EU Grant funding made available.

Applicant: Third World Resources, Energy & Environment Centre (pvt) - TWREEC

Requested budget: 3.037.255 EUR

The extended use of servers in data centers has generated an exponentially increasing request of electric power, a large fraction of which is dissipated by Joule effect and must be withdrawn to prevent device failure. The problem of keeping CPU temperature in a safe range has been approached until now as a mere heat dissipation problem managed server by server, with active dissipation requiring additional power. The rapid increase of CPU thermal budgets is now calling for disruptive solutions. GreenCPU scales the issue, seeing the large amount of heat delivered by data centers as a resource to be exploited for productive tasks. Our systemic approach integrates solutions spanning from materials science to basic physics, from biochemistry to electronic technologies: a Si-based thermoelectric cooler (TEC) is used to refrigerate water which is then used to extract heat from the CPU. TEC efficiency is enhanced by operating a pair of TECs in conjunction with thermal switches, enabling supercooling in continuous mode. The extracted heat is then transferred to a biochemical reactor where a low-temperature, safe enzymatic process of degradation of PET occurs. The system addresses two challenges at one time: (1) dissipating heat from CPUs with higher efficiency than conventional thermal management systems, which use forced air or liquid circulation; (2) reusing the large amounts of low-temperature wasted heat to tackle waste plastic accumulation in the environment. Aligned with the Twin-Transitions challenge, GreenCPU will validate the technological principles paving the way for future developments with positive economic and environmental impacts. While reducing costs for data centers thus contributing to the digital transition, GreenCPU will make two wastes - heat and plastics - to play against each other, leading to a win-win environmental solution.

Applicant: Università degli Studi di Milano Bicocca

Requested budget: 999.981,25 EUR

The EIC is successful in supporting high-tech innovation projects of various disciplines and research fields, which results into a highly fragmented portfolios of the innovation success stories. In the TECHPORT project (in short for High-TECH PORTfolio Support), our major aim is to raise the visibility and societal impact of EIC portfolios through a mix of novel, creative approaches and innovative communication tools, such as video case studies, hybrid workshops, and diverse online and gender-inclusive communities. The project approach is based on the modular concept, so as to smoothly allow for promotion of the interactions across the EIC portfolios, as well as to attract additional attention of the private capital, so as to support the smooth exit of the EIC resources and their replacement with the private capital at the very end of the life cycle of the supported innovation projects. Furthermore, with the aim to stimulate the co-creation of innovative technology visions among the supported innovative projects, as well as to discuss possible new directions for research and innovation in future deep-tech, the TECHPORT proposes to implement tailored activities and targeted actions. In order to build broad, diverse and gender-inclusive communities around each of the EIC portfolios, it is proposed to identify the key relevant stakeholders, deeply analyzing hundreds of the EIC portfolio projects and their relevant stakeholders, and actively reach out to them through tailored activities. Finally, the TECHPORT project will also target the key multiplication stakeholders in order to streamline their efforts for the benefit and sustainability of the EIC projects, as these multiplication stakeholders are seen as a key tool serving to further enhance portfolios’ societal impacts in the long-term perspective. Such proposed approach is in line with the KPI framework based on the three storylines: societal impact, economic impact and attractiveness for the private investors.

Applicant: AMBIS University

Requested budget: 2.447.012,50 EUR

HIROES is proposed within the EIC transition open call as it addresses to transfer the material innovation of the E.T. Pack project (H2020, FET-Open) into a higher TRL-Level and maturing the path for the market entry in space and medical applications. The goal is the application-oriented development and testing of the ceramic electron emitting C12A7 material as a cathode with improved properties and adapted designs of the components for integration for the application electrical space propulsion and diagnostic and therapeutic medical devices on the level of device and system integration. The efficiency and reliability of the electron emitting cathodes will be improved through the combination of reduced operation temperatures and cost saving integration in systems and devices. In space propulsion the C12A7 as emitter in cathodes will be demonstrated with reduced energy consumption and enabler for disruptive propellants. For electron sources in X-Ray-based medical diagnostics and therapies an improved emitter enhances the detection or patient dose delivery and reduce the energy consumption. The partner Fraunhofer IKTS will transfer the materiál innovation together with Airbus Space and Defence and PMB Alcen as industrial partners to a higher technological level which enables the creation of scenarios for market entries. The industry partners take over device and system integration of the C12A7- components, testing under operational conditions, market analysis and development of business cases. Innovation potential is to be enhanced by an industrial advisory board of several companies interested in electron emitting cathodes for space propulsion and medical systems. Feedback from the industrial advisory board will be incorporated in a business plan by focusing on these two markets. The consortium is supported by Grant Garant for dissemination and exploitation of the results as well as networking with innovation stakeholders and evaluation of the business plan.

Applicant: Fraunhofer Society

Requested budget: 2.322.500 EUR

Exposure to geopathic radiation (GR) is known to cause disease, but its origin and climate effects are unknown. But their origin was discovered by our experiments, which confirmed Einstein's STR, according to which matter consists of energies. Their interaction, in accordance with the laws of electrodynamics, forms a quantum electromagnetic field (QEF) in matter. Therefore, any stresses of matter cause perturbation of its QEF in the form of waves of quantum electromagnetic energy (S-radiation). As a result, quantum currents are present in the composition of electric energy during its production/storage/consumption, which is unknown to science. The technique converts them into man-made S-radiation, which pollutes the environment. For the same reason, the QEF of Earth's matter also generates S-radiation, which reveals the origin of the GR. In addition, in the S-radiation spectrum, we observed how the Earth and the Sun were occupied by the Energy Information Field (EIF) in the summer of 2003. Since then, it has been sucking Sradiation from these bodies, which has led to the processes by which polar ice taps and the activity of the Sun has decreased unprecedentedly. But at the same time, solar C-radiation contains high-temperature solar heat, which causes spontaneous combustion of plants and massive forest fires, CO2 growth and accelerates the pace of global warming. Therefore, the project concept provides, on the basis of standards and innovations, to eliminate quantum currents in electric energy at the stages of its production/storage and consumption, as well as limit the emission of S-radiation from various techniques. These measures will stop the growth of EIF, reduce CO2 and the growth of the rate of global warming, improve the environment and health.

Applicant: Academy of diagnostics, LLC

Requested budget: 3.025.655 EUR

GHG-Trap objectives are: 1. Establish a multi-actors consortium to tackle the GHG produced by intensive livestock farming. 2. Develop wearable devices (similar to masks) that can trap CO2 and CH4 gases produced by animals, such as cattle, and ensure the highest standards of animal health and well-being. 3. Develop non wearable devices (similar to air filters) for stables that can capture CO2, CH4, and N2O gases produced by cattle, sheep, goats, horses, poultry, and small livestock while the air circulation is controlled. 4. Develop adsorbents and processes that can guarantee gas trapping and subsequential elution and separation of GHG from wearable devices, without involving critical raw materials. 5. Use CO2 and CH4 gases to cultivate microorganisms and transform them in valuable goods; CO2 will be reused to boost the growth of photosynthetic microalgae; CH4 will be used to growth methanotrophic bacteria. 6. Develop a new photobioreactor for microalgae cells that can work with the not pressurized CO2 recovered from trapping devices. 7. Perform LCA and economic viability of the integrated processes. 8. Training farmers and stakeholders on good agriculture, livestock, and manure practices to reduce the emissions of CO2, CH4, and N2O and protect the environment. All the integrated solutions will use renewable energy. The design of the photobioreactor (PBR) to cultivate microalgae will be optimized in order to use only natural sun light and a very limited quantity of water (ultra-thin PBR). Bacteria will make succinic acid from CH4 released by animals and caught by wearable and non-wearable devices, which, after polymerization, will be used to create bioplastic products. From captured CO2, microalgae cells will produce valuable metabolites to be used by cosmetics, pharma and food industries. The re-generation of the developed adsorbents will be performed also with renewable electricity, using strategies like electrification, micro-waves, or magnetic fields.

Applicant: Ethnicon Metsovion Polytechnion